Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis
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چکیده
منابع مشابه
Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis
Ectopic lymphoid-like structures (ELSs) reminiscent of secondary lymphoid organs often develop at sites of chronic inflammation where they contribute to immune-mediated pathology. Through evaluation of synovial tissues from rheumatoid arthritis (RA) patients, we now show that low interleukin-27 (IL-27) expression corresponds with an increased incidence of ELS and gene signatures associated with...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2015
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.20132307